Immune EngineerOver the past decade, the focus of many bioengineers and clinicians has shifted to approaches of "immune engineering", which include but are not limited to manipulated biomaterials for vaccines, immunotherapy (immune modulation), cell and gene therapy, engineering of immune microenvironments and systems immunology. These research areas encompass an extensive list of problems associated with translational immunology, including chronic infections, autoimmune diseases, aggressive cancers, allergies, etc. The goal of the Immune Engineering SIG is to bring together new ideas and provide a venue for professional interaction with a wide range of academic and industrial research groups and scientists working in these fields.
The human immune system is highly multifaceted and incredibly fascinating. Immune cells typically act in complex microenvironments which has important implications for immunotherapy. The high level of plasticity is achieved by a wide range of signalling molecules, cell types and specialized subtypes. Successful immunotherapy against cancer, auto-immune and infectious diseases is the result of a multitude of cellular interactions within the immune system.
The core challenge of my group is a systems immunology approach to develop and apply innovative engineering tools to study the immune system in health and disease, and to create new or improve existing therapies by enhancing or modulating immune responses.
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